Cancer induces cardiomyocyte remodeling and hypoinnervation in the left ventricle of the mouse heart.

Cancer is often associated with cachexia, cardiovascular symptoms and autonomic dysregulation. We tested whether extracardiac cancer directly affects the innervation of left ventricular myocardium. Mice injected with Lewis lung carcinoma cells (tumor group, TG) or PBS (control group, CG) were analyz...

Full description

Bibliographic Details
Main Authors: Christian Mühlfeld, Suman Kumar Das, Frank R Heinzel, Albrecht Schmidt, Heiner Post, Silvia Schauer, Tamara Papadakis, Wolfgang Kummer, Gerald Hoefler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21637823/?tool=EBI