QSAR modeling of antimalarial activity of urea derivatives using genetic algorithm–multiple linear regressions

QSAR modeling of antimalarial activity of urea derivatives using genetic algorithm–multiple linear regressions

A quantitative structure–activity relationship (QSAR) was performed to analyze antimalarial activities of 68 urea derivatives using multiple linear regressions (MLR). QSAR analyses were performed on the available 68 IC50 oral data based on theoretical molecular descriptors. A suitable set of molecul...

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Bibliographic Details
Main Authors: Abolghasem Beheshti, Eslam Pourbasheer, Mehdi Nekoei, Saadat Vahdani
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Journal of Saudi Chemical Society
Subjects:
QSAR
Genetic algorithm
Multiple linear regression
Antimalarial
Urea derivatives
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610312001287

Internet

http://www.sciencedirect.com/science/article/pii/S1319610312001287

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