HFIP-Promoted Bischler Indole Synthesis under Microwave Irradiation

1,1,1,3,3,3-Hexafluoropropan-2-ol (HFIP) was found to be effective for the Bischler indole synthesis under microwave irradiation in the absence of a metal catalyst. Under the catalysis of HFIP, a wide range of α-amino arylacetones were successfully transformed into indole derivatives with m...

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Bibliographic Details
Main Authors: Guangkai Yao, Zhi-Xiang Zhang, Cheng-Bei Zhang, Han-Hong Xu, Ri-Yuan Tang
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/23/12/3317