A surfactant polymer wound dressing protects human keratinocytes from inducible necroptosis

Abstract Chronic wounds show necroptosis from which keratinocytes must be protected to enable appropriate wound re-epithelialization and closure. Poloxamers, a class of synthetic triblock copolymers, are known to be effective against plasma membrane damage (PMD). The purpose of this study is to eval...

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Bibliographic Details
Main Authors: Puneet Khandelwal, Amitava Das, Chandan K. Sen, Sangly P. Srinivas, Sashwati Roy, Savita Khanna
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82260-x