Mutations in HPV18 E1^E4 Impact Virus Capsid Assembly, Infectivity Competence, and Maturation

The most highly expressed protein during the productive phase of the human papillomavirus (HPV) life cycle is E1^E4. Its full role during infection remains to be established. HPV E1^E4 is expressed during both the early and late stages of the virus life cycle and contributes to viral genome amplific...

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Bibliographic Details
Main Authors: Jennifer Biryukov, Jocelyn C. Myers, Margaret E. McLaughlin-Drubin, Heather M. Griffin, Janice Milici, John Doorbar, Craig Meyers
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/9/12/385