CRBN knockdown mitigates lipopolysaccharide-induced acute lung injury by suppression of oxidative stress and endoplasmic reticulum (ER) stress associated NF-κB signaling
Acute lung injury (ALI) is a common clinical disorder, resulting in substantial health problems in the world. However, the molecular mechanism that contributes to ALI is still unclear. Cereblon (CRBN) has recently been identified as a target for immunomodulatory drugs, playing a critical role in reg...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-03-01
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| Series: | Biomedicine & Pharmacotherapy |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332219353831 |