Mammalian Cell Culture Clarification: A Case Study Using Chimeric Anti-CEA Monoclonal Antibodies
The extracellular expression of monoclonal antibodies (mAbs) in mammalian cell culture provides both opportunities and restrictions for the design of robust harvest and clarification operations. With advances in cell culture media and cell lines, it is now possible to achieve high titers of over 5...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
IIUM Press, International Islamic University Malaysia
2011-12-01
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Series: | International Islamic University Malaysia Engineering Journal |
Online Access: | http://journals.iium.edu.my/ejournal/index.php/iiumej/article/view/236 |