CLEC2 and CLEC5A: Pathogenic Host Factors in Acute Viral Infections

The protective roles of endosomal toll-like receptors (TLRs) and cytosolic nucleic acid sensors are well elucidated, but the pathogenic host factors during viral infections remain unclear. Spleen tyrosine kinase (Syk)-coupled C-type lectins (CLECs) CLEC2 and CLEC5A are highly expressed on platelets...

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Bibliographic Details
Main Authors: Pei-Shan Sung, Shie-Liang Hsieh
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Immunology
Subjects:
Syk
TLR
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02867/full