A latent model for prioritization of SNPs for functional studies.

One difficult question facing researchers is how to prioritize SNPs detected from genetic association studies for functional studies. Often a list of the top M SNPs is determined based on solely the p-value from an association analysis, where M is determined by financial/time constraints. For many s...

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Bibliographic Details
Main Authors: Brooke L Fridley, Ed Iversen, Ya-Yu Tsai, Gregory D Jenkins, Ellen L Goode, Thomas A Sellers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3110798?pdf=render