Imaging incorporation of circulating docosahexaenoic acid into the human brain using positron emission tomography

Imaging incorporation of circulating docosahexaenoic acid into the human brain using positron emission tomography

Docosahexaenoic acid (DHA; 22:6n-3) is a critical constituent of the brain, but its metabolism has not been measured in the human brain in vivo. In monkeys, using positron emission tomography (PET), we first showed that intravenously injected [1-11C]DHA mostly entered nonbrain organs, with ∼0.5% ent...

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Bibliographic Details
Main Authors: John C. Umhau, Weiyin Zhou, Richard E. Carson, Stanley I. Rapoport, Alla Polozova, James Demar, Nahed Hussein, Abesh K. Bhattacharjee, Kaizong Ma, Giuseppe Esposito, Sharon Majchrzak, Peter Herscovitch, William C. Eckelman, Karen A. Kurdziel, Norman Salem, Jr.
Format: Article
Language:English
Published: Elsevier 2009-07-01
Series:Journal of Lipid Research
Subjects:
metabolism
blood flow
n-3 polyunsaturated fatty acid
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520307756

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http://www.sciencedirect.com/science/article/pii/S0022227520307756

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