Antimicrobial peptide GH12 suppresses cariogenic virulence factors of Streptococcus mutans

Antimicrobial peptide GH12 suppresses cariogenic virulence factors of Streptococcus mutans

Cariogenic virulence factors of Streptococcus mutans include acidogenicity, aciduricity, and extracellular polysaccharides (EPS) synthesis. The de novo designed antimicrobial peptide GH12 has shown bactericidal effects on S. mutans, but its interaction with virulence and regulatory systems of S. mut...

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Bibliographic Details
Main Authors: Yufei Wang, Xiuqing Wang, Wentao Jiang, Kun Wang, Junyuan Luo, Wei Li, Xuedong Zhou, Linglin Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Journal of Oral Microbiology
Subjects:
Dental caries
antimicrobial cationic peptides
anti-bacterial agents
acidogenicity
aciduricity
biofilms
Online Access:http://dx.doi.org/10.1080/20002297.2018.1442089

Internet

http://dx.doi.org/10.1080/20002297.2018.1442089

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