pH value monitoring during human albumin purification with near infrared spectroscopy and chemometrics

Human albumin (HA) is a very important blood product which requires strict quality control strategy. Acid precipitation is a key step which has a great effect on the quality of final product. Therefore, a new method based on quality by design (QbD) was proposed to investigate the feasibility of real...

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Bibliographic Details
Main Authors: Qiaofeng Sun, Zhongyu Sun, Fei Wang, Lian Li, Ronghua Liu, Lei Nie, Jiayue Wang, Mingyu Wang, Hengchang Zang
Format: Article
Language:English
Published: World Scientific Publishing 2018-05-01
Series:Journal of Innovative Optical Health Sciences
Subjects:
Online Access:http://www.worldscientific.com/doi/pdf/10.1142/S1793545818500098