Parvovirus B19 Nonstructural Protein-Induced Damage of Cellular DNA and Resultant Apoptosis
<p>Parvovirus B19 is a widespread virus with diverse clinical presentations. The viral nonstructural protein, NS1, binds to and cleaves the viral genome, and induces apoptosis when transfected into nonpermissive cells, such as hepatocytes. We hypothesized that the cytotoxicity of NS1 in such c...
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| Format: | Article |
| Language: | English |
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Ivyspring International Publisher
2011-01-01
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| Series: | International Journal of Medical Sciences |
| Online Access: | http://www.medsci.org/v08p0088.htm |