Human Umbilical Cord Mesenchymal Stem Cells Support Nontumorigenic Expansion of Human Embryonic Stem Cells

The expansion of pluripotent human embryonic stem cells (hESCs) requires a culture on feeder layers of mouse embryonic fibroblasts (MEFs). The culture model often causes immunogenic contaminations such as xenocarbohydrate, and inevitably forms teratoma in vivo. This study tested human umbilical cord...

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Bibliographic Details
Main Authors: Dah-Ching Ding, Woei-Cherng Shyu, Shinn-Zong Lin, Hwan-Wun Liu, Shih-Hwa Chiou, Tang-Yuan Chu M.D., Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2012-07-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368912X647199