Clinical utility of activated partial thromboplastin time clot waveform analysis and thrombin generation test in the evaluation of bleeding phenotype in Hemophilia A

Clinical utility of activated partial thromboplastin time clot waveform analysis and thrombin generation test in the evaluation of bleeding phenotype in Hemophilia A

Context: Hemophilia A is classified as mild, moderate, and severe based on Factor VIII levels (FVIII). Clot-based assays only detect initiation of thrombin generation, hence FVIII levels may not accurately predict the bleeding risk in all hemophilia patients. The entire process of thrombin generatio...

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Bibliographic Details
Main Authors: Rutvi G Dave, Tulasi Geevar, Joy J Mammen, Ramya Vijayan, Gowri Mahasampath, Sukesh C Nair
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
clot waveform analysis
factor viii
hemophilia a
international society of thrombosis and haemostasis-bleeding assessment tool score
thrombin generation test
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2021;volume=64;issue=1;spage=117;epage=122;aulast=Dave

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http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2021;volume=64;issue=1;spage=117;epage=122;aulast=Dave

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