Gallic Acid Inhibits Lipid Accumulation via AMPK Pathway and Suppresses Apoptosis and Macrophage-Mediated Inflammation in Hepatocytes

Gallic Acid Inhibits Lipid Accumulation via AMPK Pathway and Suppresses Apoptosis and Macrophage-Mediated Inflammation in Hepatocytes

Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease, sometimes ranges from simple steatosis to nonalcoholic steatohepatitis (NASH). Various hits including excessive hepatic steatosis, oxidative stress, apoptosis, and inflammation, contribute to NASH dev...

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Bibliographic Details
Main Authors: Miori Tanaka, Akari Sato, Yoshimi Kishimoto, Hideaki Mabashi-Asazuma, Kazuo Kondo, Kaoruko Iida
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Nutrients
Subjects:
gallic acid
polyphenol
nonalcoholic steatohepatitis
hepatocyte
macrophage
Online Access:https://www.mdpi.com/2072-6643/12/5/1479

Internet

https://www.mdpi.com/2072-6643/12/5/1479

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