Homology modeling and docking studies of Plasmodium falciparum telomerase reverse transcriptase with berberine and some of its derivatives

The telomerase reverse transcriptase (TERT) sequence from Plasmodium falciparum provides valuable information for the design of specific anti-telomerase drugs. The present study deals with the interaction of pfTERT against berberine derivatives to derive novel analogues. Berberine intercalates DNA,...

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Bibliographic Details
Main Authors: Pratap Parida, Samhita Kalita, R. N. S. Yadav, Brajesh Shankar
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2014-02-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Online Access:https://www.banglajol.info/index.php/BJP/article/view/17535