Bactericidal fully human single‐chain fragment variable antibodies protect mice against methicillin‐resistant Staphylococcus aureus bacteraemia

Bactericidal fully human single‐chain fragment variable antibodies protect mice against methicillin‐resistant Staphylococcus aureus bacteraemia

Abstract Objectives The increasing prevalence of antibiotic‐resistant Staphylococcus aureus, besides the inadequate numbers of effective antibiotics, emphasises the need to find new therapeutic agents against this lethal pathogen. Methods In this study, to obtain antibody fragments against S. aureus...

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Bibliographic Details
Main Authors: Behnoush Soltanmohammadi, Somayeh Piri‐Gavgani, Eilnaz Basardeh, Mostafa Ghanei, Masoumeh Azizi, Zabihollah Khaksar, Zahra Sharifzadeh, Farzad Badmasti, Mahdieh Soezi, Abolfazl Fateh, Parisa Azimi, Seyed Davar Siadat, Fahimeh Shooraj, Saeid Bouzari, Mir Davood Omrani, Fatemeh Rahimi‐Jamnani
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical & Translational Immunology
Subjects:
bacteraemia
bactericidal antibodies
fully human antibody
methicillin‐resistant Staphylococcus aureus
single‐chain fragment variable
Online Access:https://doi.org/10.1002/cti2.1302

Internet

https://doi.org/10.1002/cti2.1302

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