Spectral Dynamics of Resting State fMRI Within the Ventral Tegmental Area and Dorsal Raphe Nuclei in Medication-Free Major Depressive Disorder in Young Adults

Spectral Dynamics of Resting State fMRI Within the Ventral Tegmental Area and Dorsal Raphe Nuclei in Medication-Free Major Depressive Disorder in Young Adults

Background: Dorsal raphe nucleus (DRN) and ventral tegmental area (VTA) are major brainstem monamine nuclei consisting of serotonin and dopamine neurons respectively. Animal studies show that firing patterns in both nuclei are altered when animals exhibit depression like behaviors. Functional MRI st...

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Bibliographic Details
Main Authors: Afra Wohlschläger, Harish Karne, Denis Jordan, Mark J. Lowe, Stephen E. Jones, Amit Anand
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Psychiatry
Subjects:
dorsal raphe nucleus
ventral tegmental nucleus
resting state fMRI
resting state
serotonin
dopamine
Online Access:http://journal.frontiersin.org/article/10.3389/fpsyt.2018.00163/full

Internet

http://journal.frontiersin.org/article/10.3389/fpsyt.2018.00163/full

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