Pro-inflammatory adjuvant properties of pigment-grade titanium dioxide particles are augmented by a genotype that potentiates interleukin 1β processing

Pro-inflammatory adjuvant properties of pigment-grade titanium dioxide particles are augmented by a genotype that potentiates interleukin 1β processing

Abstract Background Pigment-grade titanium dioxide (TiO2) particles are an additive to some foods (E171 on ingredients lists), toothpastes, and pharma−/nutraceuticals and are absorbed, to some extent, in the human intestinal tract. TiO2 can act as a modest adjuvant in the secretion of the pro-inflam...

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Bibliographic Details
Main Authors: Sebastian Riedle, Laetitia C. Pele, Don E. Otter, Rachel E. Hewitt, Harjinder Singh, Nicole C. Roy, Jonathan J. Powell
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Particle and Fibre Toxicology
Subjects:
Nano
Particle
TiO2
E171
NOD2
IL-1β
Online Access:http://link.springer.com/article/10.1186/s12989-017-0232-2

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http://link.springer.com/article/10.1186/s12989-017-0232-2

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