Pro-inflammatory adjuvant properties of pigment-grade titanium dioxide particles are augmented by a genotype that potentiates interleukin 1β processing
Abstract Background Pigment-grade titanium dioxide (TiO2) particles are an additive to some foods (E171 on ingredients lists), toothpastes, and pharma−/nutraceuticals and are absorbed, to some extent, in the human intestinal tract. TiO2 can act as a modest adjuvant in the secretion of the pro-inflam...
Main Authors: | Sebastian Riedle, Laetitia C. Pele, Don E. Otter, Rachel E. Hewitt, Harjinder Singh, Nicole C. Roy, Jonathan J. Powell |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-12-01
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Series: | Particle and Fibre Toxicology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12989-017-0232-2 |
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