KLF10 integrates circadian timing and sugar signaling to coordinate hepatic metabolism

KLF10 integrates circadian timing and sugar signaling to coordinate hepatic metabolism

The mammalian circadian timing system and metabolism are highly interconnected, and disruption of this coupling is associated with negative health outcomes. Krüppel-like factors (KLFs) are transcription factors that govern metabolic homeostasis in various organs. Many KLFs show a circadian expressio...

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Bibliographic Details
Main Authors: Anthony A Ruberto, Aline Gréchez-Cassiau, Sophie Guérin, Luc Martin, Johana S Revel, Mohamed Mehiri, Malayannan Subramaniam, Franck Delaunay, Michèle Teboul
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-08-01
Series:eLife
Subjects:
circadian rhythm
metabolism
krüppel like factors
liver
fructose
glucose
Online Access:https://elifesciences.org/articles/65574

Internet

https://elifesciences.org/articles/65574

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