Prenatal intestinal obstruction affects the myenteric plexus and causes functional bowel impairment in fetal rat experimental model of intestinal atresia.

BACKGROUND: Intestinal atresia is a rare congenital disorder with an incidence of 3/10,000 birth. About one-third of patients have severe intestinal dysfunction after surgical repair. We examined whether prenatal gastrointestinal obstruction might effect on the myenteric plexus and account for subse...

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Main Authors: Naziha Khen-Dunlop, Sabine Sarnacki, Anais Victor, Celine Grosos, Sandrine Menard, Rodolphe Soret, Nicolas Goudin, Maud Pousset, Frederique Sauvat, Yann Revillon, Nadine Cerf-Bensussan, Michel Neunlist
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3648556?pdf=render