A Novel Self-Emulsifying Drug Delivery System (SEDDS) Based on VESIsorb<sup>®</sup> Formulation Technology Improving the Oral Bioavailability of Cannabidiol in Healthy Subjects

A Novel Self-Emulsifying Drug Delivery System (SEDDS) Based on VESIsorb<sup>®</sup> Formulation Technology Improving the Oral Bioavailability of Cannabidiol in Healthy Subjects

Cannabidiol (CBD), a phytocannabinoid compound of <i>Cannabis sativa</i>, shows limited oral bioavailability due to its lipophilicity and extensive first-pass metabolism. CBD is also known for its high intra- and inter-subject absorption variability in humans. To overcome these limitatio...

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Bibliographic Details
Main Authors: Katharina Knaub, Tina Sartorius, Tanita Dharsono, Roland Wacker, Manfred Wilhelm, Christiane Schön
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Molecules
Subjects:
bioavailability
<i>Cannabis sativa</i>
cannabidiol
CBD
hemp extract
human
oral drug delivery system
pharmacokinetic
SEDDS
Online Access:https://www.mdpi.com/1420-3049/24/16/2967

Internet

https://www.mdpi.com/1420-3049/24/16/2967

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