NDUFB6 Polymorphism Is Associated With Physical Activity-Mediated Metabolic Changes in Type 2 Diabetes

NDUFB6 Polymorphism Is Associated With Physical Activity-Mediated Metabolic Changes in Type 2 Diabetes

The rs540467 SNP in the NDUFB6 gene, encoding a mitochondrial complex I subunit, has been shown to modulate adaptations to exercise training. Interaction effects with diabetes mellitus remain unclear. We assessed associations of habitual physical activity (PA) levels with metabolic variables and exa...

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Bibliographic Details
Main Authors: Dominik Pesta, Tomas Jelenik, Oana-Patricia Zaharia, Pavel Bobrov, Sven Görgens, Kálmán Bódis, Yanislava Karusheva, Nina Krako Jakovljevic, Nebojsa M. Lalic, Daniel F. Markgraf, Volker Burkart, Karsten Müssig, Birgit Knebel, Jörg Kotzka, Jürgen Eckel, Klaus Strassburger, Julia Szendroedi, Michael Roden
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Endocrinology
Subjects:
diabetes mellitus
physical activity
single nucleotide polymorphism
insulin sensitivity
mitochondrial function
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.693683/full

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https://www.frontiersin.org/articles/10.3389/fendo.2021.693683/full

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