Early-life adversity facilitates acquisition of cocaine self-administration and induces persistent anhedonia
Early-life adversity increases the risk for emotional disorders such as depression and schizophrenia. Anhedonia, thought to be a core feature of these disorders, is provoked by our naturalistic rodent model of childhood adversity (i.e., rearing pups for one week in cages with limited bedding and nes...
Main Authors: | Jessica L. Bolton, Christina M. Ruiz, Neggy Rismanchi, Gissell A. Sanchez, Erik Castillo, Jeff Huang, Christopher Cross, Tallie Z. Baram, Stephen V. Mahler |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2018-02-01
|
Series: | Neurobiology of Stress |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352289517300401 |
Similar Items
-
Anhedonia in cocaine use disorder is associated with inflammatory gene expression.
by: Gabriel Rodrigo Fries, et al.
Published: (2018-01-01) -
La anhedonia
by: Héctor Perez-Rincón
Published: (2014-12-01) -
A novel mouse model for vulnerability to alcohol dependence induced by early-life adversity
by: Agbonlahor Okhuarobo, et al.
Published: (2020-11-01) -
The Developmental Origins of Opioid Use Disorder and Its Comorbidities
by: Sophia C. Levis, et al.
Published: (2021-02-01) -
Ventral Subiculum Stimulation Promotes Persistent Hyperactivity of Dopamine Neurons and Facilitates Behavioral Effects of Cocaine
by: Christelle Glangetas, et al.
Published: (2015-12-01)