MicroRNA-550a acts as a pro-metastatic gene and directly targets cytoplasmic polyadenylation element-binding protein 4 in hepatocellular carcinoma.

MicroRNAs (miRNAs) are a class of small, non-coding RNA molecules that are often found at chromosomal breakpoints and play a vital role in human cancer. Our previous study found that miR-550a, a frequently amplified miRNA on 7p14.3, was upregulated in hepatocellular carcinoma (HCC). However, the pos...

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Bibliographic Details
Main Authors: Qi Tian, Linhui Liang, Jie Ding, Ruopeng Zha, Haibing Shi, Qifeng Wang, Shenglin Huang, Weijie Guo, Chao Ge, Taoyang Chen, Jinjun Li, Xianghuo He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3492136?pdf=render