Mitochondrial inhibitory factor 1 (IF1) is present in human serum and is positively correlated with HDL-cholesterol.

<h4>Background</h4>Mitochondrial ATP synthase is expressed as a plasma membrane receptor for apolipoprotein A-I (apoA-I), the major protein component in High Density Lipoproteins (HDL). On hepatocytes, apoA-I binds to cell surface ATP synthase (namely ecto-F(1)-ATPase) and stimulates its...

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Main Authors: Annelise Genoux, Véronique Pons, Claudia Radojkovic, Florence Roux-Dalvai, Guillaume Combes, Corinne Rolland, Nicole Malet, Bernard Monsarrat, Frédéric Lopez, Jean-Bernard Ruidavets, Bertrand Perret, Laurent O Martinez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21935367/?tool=EBI