Effects of Vitamin K2 on the Expression of Genes Involved in Bile Acid Synthesis and Glucose Homeostasis in Mice with Humanized PXR

Effects of Vitamin K2 on the Expression of Genes Involved in Bile Acid Synthesis and Glucose Homeostasis in Mice with Humanized PXR

Pregnane X receptor (PXR) is a nuclear receptor activated by various compounds, including prescribed drugs and dietary ingredients. Ligand-specific activation of PXR alters drug metabolism and affects many other physiological conditions. Species-specific ligand preference is a considerable challenge...

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Bibliographic Details
Main Authors: Halima Sultana, Kimika Watanabe, Md Masud Rana, Rie Takashima, Ai Ohashi, Michio Komai, Hitoshi Shirakawa
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Nutrients
Subjects:
PXR
menaquinone 4
bile homeostasis
energy homeostasis
gene expression
Online Access:http://www.mdpi.com/2072-6643/10/8/982

Internet

http://www.mdpi.com/2072-6643/10/8/982

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