The Effect of Metformin and GANT61 Combinations on the Radiosensitivity of Prostate Cancer Cells
The anti-diabetes drug metformin has been shown to have anti-neoplastic effects in several tumor models through its effects on energy metabolism and protein synthesis. Recent studies show that metformin also targets Hedgehog (Hh) signaling, a developmental pathway re-activated in several tumor types...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-02-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/18/2/399 |