Quantitative Structure Inter-Activity Relationship (QSInAR). Cytotoxicity Study of Some Hemisynthetic and Isolated Natural Steroids and Precursors on Human Fibrosarcoma Cells HT1080

Quantitative Structure Inter-Activity Relationship (QSInAR). Cytotoxicity Study of Some Hemisynthetic and Isolated Natural Steroids and Precursors on Human Fibrosarcoma Cells HT1080

Combined experimental and quantitative structure inter-activity relationship (QSIAR) computation methods were advanced in order to establish the structural and mechanistic influences that steroids and triterpenes, either as newly synthesized or naturally isolated products, have on human HT1080 mamma...

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Bibliographic Details
Main Authors: Marius Lazea, Louis P. Sandjo, Mihai V. Putz
Format: Article
Language:English
Published: MDPI AG 2011-08-01
Series:Molecules
Subjects:
steroids and triterpenes
organic synthesis
HT1080 cancer cell lines
cytotoxicity activity
Hansch indices
mono and multi-linear correlations
Online Access:http://www.mdpi.com/1420-3049/16/8/6603/

Internet

http://www.mdpi.com/1420-3049/16/8/6603/

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