Growth Differentiation Factor-11 Causes Neurotoxicity During Ischemia in vitro

Growth Differentiation Factor-11 Causes Neurotoxicity During Ischemia in vitro

Age-related neuronal dysfunction can be overcome by circulating factors present in young blood. Growth differentiation factor-11 (GDF-11), a systemic factor that declines with age, can reverse age-related dysfunction in brain, heart and skeletal muscle. Given that age increases susceptibility to str...

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Bibliographic Details
Main Authors: Brad A. Sutherland, Gina Hadley, Zoi Alexopoulou, Tiffany A. Lodge, Ain A. Neuhaus, Yvonne Couch, Nareg Kalajian, Karl J. Morten, Alastair M. Buchan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Neurology
Subjects:
growth factor
GDF-11
stroke
neuron
ischemia
in vitro
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.01023/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.01023/full

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