Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus.
Systemic lupus erythematosus (SLE) is a genetically complex disease with heterogeneous clinical manifestations. A polymorphism in the STAT4 gene has recently been established as a risk factor for SLE, but the relationship with specific SLE subphenotypes has not been studied. We studied 137 SNPs in t...
Main Authors: | , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-05-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2377340?pdf=render |