Binding of DC-SIGN to the hemagglutinin of influenza A viruses supports virus replication in DC-SIGN expressing cells.

Binding of DC-SIGN to the hemagglutinin of influenza A viruses supports virus replication in DC-SIGN expressing cells.

Dendritic cells express lectins receptors, like DC-SIGN, which allow these cells to sense glycans that are present on various bacterial and viral pathogens. Interaction of DC-SIGN with carbohydrate moieties induces maturation of dendritic cells and promotes endocytosis of pathogens which is an impor...

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Bibliographic Details
Main Authors: Marine L B Hillaire, Nella J Nieuwkoop, Adrianus C M Boon, Gerrie de Mutsert, Stella E Vogelzang-van Trierum, Ron A M Fouchier, Albert D M E Osterhaus, Guus F Rimmelzwaan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3570528?pdf=render

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http://europepmc.org/articles/PMC3570528?pdf=render

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