The anti-inflammatory function of HDL is impaired in type 2 diabetes: role of hyperglycemia, paraoxonase-1 and low grade inflammation

Abstract Background Functional properties of high density lipoproteins (HDL) are increasingly recognized to play a physiological role in atheroprotection. Type 2 diabetes mellitus (T2DM) is characterized by low HDL cholesterol, but the effect of chronic hyperglycemia on the anti-inflammatory capacit...

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Bibliographic Details
Main Authors: Sanam Ebtehaj, Eke G. Gruppen, Mojtaba Parvizi, Uwe J. F. Tietge, Robin P. F. Dullaart
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Cardiovascular Diabetology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12933-017-0613-8