Клінічні особливості реактивних артритів у дітей
. Reactive arthritis includes inflammatory non-purulent diseases of the joints that develop within 2-4 weeks after intestinal or urogenital infection due to immune disorders. Given the nonspecificity of the clinical manifestations of reactive arthritis, its similarity to other rheumatic diseases, wh...
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V.N. Karazin Kharkov National University
2020-12-01
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doaj-fa3ccc2bdb2a47458db04e3662b909202020-12-30T08:22:49ZengV.N. Karazin Kharkov National UniversityАктуальні проблеми сучасної медицини2617-409X2020-12-0162633https://doi.org/10.26565/2617-409X-2020-6-04Клінічні особливості реактивних артритів у дітейNataliya Panko0https://orcid.org/0000-0002-3200-8942Iryna Lebets1https://orcid.org/0000-0003-0050-2898Natalia Shevchenko2https://orcid.org/0000-0003-4407-6050Oksana Tsiura3https://orcid.org/0000-0001-8245-015XHanna Shlieienkova4https://orcid.org/0000-0001-9775-4324Antonina Butenko5к. мед. н., доц. кафедри педіатрії № 2 Харківського національного університету імені В. Н. Каразінад. мед. н., проф., кафедри педіатрії Харківського національного університету імені В. Н. Каразіна, пров. наук. співроб. відділення кардіоревматології ДУ «Інститут охорони здоров’я дітей та підлітків НАМН»д. мед. н., зав. кафедрою педіатрії № 2 Харківського національного університету імені В. Н. Каразінак. мед. н, доцент кафедри педіатрії № 2 Харківського національного університету імені В. Н. Каразінак. мед. н., асистент кафедри педіатрії № 2 Харківського національного університету імені В.Н. Каразінак. мед. наук, доц. кафедри педіатрії № 2 Харківського національного університету імені В. Н. Каразіна. Reactive arthritis includes inflammatory non-purulent diseases of the joints that develop within 2-4 weeks after intestinal or urogenital infection due to immune disorders. Given the nonspecificity of the clinical manifestations of reactive arthritis, its similarity to other rheumatic diseases, which have a more unfavorable course and prognosis, it must be recognized that the problem of reactive arthritis in children remains relevant and on many issues not developed. Objective: this is to identify the characteristics of the debut and currents of reactive arthritis in accordance to etiology in children today. Materials and methods: There were observed 81 children with a reactive arthritis in the age of from 2 till 17 years have been examined. During specification the nosology of articular pathology were used clinical, laboratory and instrumental investigations, identified specific antibodies to Chlamydia, Mycoplasma, Iersiniya, Ureaplazma, Citomegalovirus, Herpes simplex virus, Epstein-Bar’s virus by ELISA. Results: For reactive arthritis chlamydial etiology characterized by loss of large and medium-sized joints of the lower limbs, which often is accompanied by a brief morning stiffness and rapid emergence of transient regional hypotrophy of muscles. Feature ureaplazmial reactive arthritis is the formation of bursitis in the heel and tendinitis. Reactive arthritis, which is accompanied by elevated titers to ASL-O, had different polymorphisms of articular manifestations of the syndrome and to a certain degree of similarity with juvenile rheumatoid arthritis. Reactive arthritis of not specified etiology has a number of the general features with others reactive arthritis and it is characterized by rather good-quality current, long conservation of function of joints and low laboratory activity. Conclusions: The clinical manifestation of the disease and the nature of its course to some extent depend on the etiological pathogen of arthritis. The most unfavorable variants of reactive arthritis are arthritides caused by Chlamydia and Mycoplasma. Regardless of the pathogen, the infectious factor can be assessed as a trigger for the development of juvenile rheumatoid arthritis. The presence of recurrent reactive arthritis is the basis for re-differential diagnosis and reclassification of reactive arthritis in favor of juvenile rheumatoid arthritis, despite the low degree of inflammatory activity of the disease and ANA and HLAB27 negativity.https://periodicals.karazin.ua/apmm/article/view/16642reactive arthritischildhood agechlamidiamycoplasmaureaplasma |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Nataliya Panko Iryna Lebets Natalia Shevchenko Oksana Tsiura Hanna Shlieienkova Antonina Butenko |
spellingShingle |
Nataliya Panko Iryna Lebets Natalia Shevchenko Oksana Tsiura Hanna Shlieienkova Antonina Butenko Клінічні особливості реактивних артритів у дітей Актуальні проблеми сучасної медицини reactive arthritis childhood age chlamidia mycoplasma ureaplasma |
author_facet |
Nataliya Panko Iryna Lebets Natalia Shevchenko Oksana Tsiura Hanna Shlieienkova Antonina Butenko |
author_sort |
Nataliya Panko |
title |
Клінічні особливості реактивних артритів у дітей |
title_short |
Клінічні особливості реактивних артритів у дітей |
title_full |
Клінічні особливості реактивних артритів у дітей |
title_fullStr |
Клінічні особливості реактивних артритів у дітей |
title_full_unstemmed |
Клінічні особливості реактивних артритів у дітей |
title_sort |
клінічні особливості реактивних артритів у дітей |
publisher |
V.N. Karazin Kharkov National University |
series |
Актуальні проблеми сучасної медицини |
issn |
2617-409X |
publishDate |
2020-12-01 |
description |
. Reactive arthritis includes inflammatory non-purulent diseases of the joints that develop within 2-4 weeks after intestinal or urogenital infection due to immune disorders. Given the nonspecificity of the clinical manifestations of reactive arthritis, its similarity to other rheumatic diseases, which have a more unfavorable course and prognosis, it must be recognized that the problem of reactive arthritis in children remains relevant and on many issues not developed. Objective: this is to identify the characteristics of the debut and currents of reactive arthritis in accordance to etiology in children today. Materials and methods: There were observed 81 children with a reactive arthritis in the age of from 2 till 17 years have been examined. During specification the nosology of articular pathology were used clinical, laboratory and instrumental investigations, identified specific antibodies to Chlamydia, Mycoplasma, Iersiniya, Ureaplazma, Citomegalovirus, Herpes simplex virus, Epstein-Bar’s virus by ELISA. Results: For reactive arthritis chlamydial etiology characterized by loss of large and medium-sized joints of the lower limbs, which often is accompanied by a brief morning stiffness and rapid emergence of transient regional hypotrophy of muscles. Feature ureaplazmial reactive arthritis is the formation of bursitis in the heel and tendinitis. Reactive arthritis, which is accompanied by elevated titers to ASL-O, had different polymorphisms of articular manifestations of the syndrome and to a certain degree of similarity with juvenile rheumatoid arthritis. Reactive arthritis of not specified etiology has a number of the general features with others reactive arthritis and it is characterized by rather good-quality current, long conservation of function of joints and low laboratory activity. Conclusions: The clinical manifestation of the disease and the nature of its course to some extent depend on the etiological pathogen of arthritis. The most unfavorable variants of reactive arthritis are arthritides caused by Chlamydia and Mycoplasma. Regardless of the pathogen, the infectious factor can be assessed as a trigger for the development of juvenile rheumatoid arthritis. The presence of recurrent reactive arthritis is the basis for re-differential diagnosis and reclassification of reactive arthritis in favor of juvenile rheumatoid arthritis, despite the low degree of inflammatory activity of the disease and ANA and HLAB27 negativity. |
topic |
reactive arthritis childhood age chlamidia mycoplasma ureaplasma |
url |
https://periodicals.karazin.ua/apmm/article/view/16642 |
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