Human Serum Albumin Conjugates of 7-Ethyl-10-hydroxycamptothecin (SN38) for Cancer Treatment

SN38 (7-ethyl-10-hydroxy-comptothecin) is a potent metabolite of irinotecan, which has been approved for treatment of metastatic colorectal cancer. Considering the notable potency of SN38, it has been introduced as an anticancer candidate. In this study, human serum albumin (HSA) conjugates of SN38...

Full description

Bibliographic Details
Main Authors: Nima Sepehri, Hasti Rouhani, Ahmad Reza Ghanbarpour, Mehdi Gharghabi, Faranak Tavassolian, Mohsen Amini, Seyed Nasser Ostad, Mohammad Hossein Ghahremani, Rassoul Dinarvand
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/963507