A Simple Three-Dimensional In Vitro Culture Mimicking the In Vivo-Like Cell Behavior of Bladder Patient-Derived Xenograft Models

A Simple Three-Dimensional In Vitro Culture Mimicking the In Vivo-Like Cell Behavior of Bladder Patient-Derived Xenograft Models

Patient-derived xenograft (PDX) models allow for personalized drug selection and the identification of drug resistance mechanisms in cancer cells. However, PDX models present technical disadvantages, such as long engraftment time, low success rate, and high maintenance cost. On the other hand, tumor...

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Bibliographic Details
Main Authors: Robson Amaral, Maike Zimmermann, Ai-Hong Ma, Hongyong Zhang, Kamilla Swiech, Chong-Xian Pan
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
3D cell culture
PDX models
tumor spheroids
bladder cells
ultra-low attachment plates
Matrigel
Online Access:https://www.mdpi.com/2072-6694/12/5/1304

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https://www.mdpi.com/2072-6694/12/5/1304

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