Two Amphioxus ApeC-Containing Proteins Bind to Microbes and Inhibit the TRAF6 Pathway

Two Amphioxus ApeC-Containing Proteins Bind to Microbes and Inhibit the TRAF6 Pathway

The apextrin C-terminal (ApeC) domain is a class of newly discovered protein domains with an origin dating back to prokaryotes. ApeC-containing proteins (ACPs) have been found in various marine and aquatic invertebrates, but their functions and the underlying mechanisms are largely unknown. Early st...

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Bibliographic Details
Main Authors: Jin Li, Yuhui Li, Zhaoyu Fan, Shenghui Chen, Xinyu Yan, Zirui Yue, Guangrui Huang, Shumin Liu, Hao Zhang, Shangwu Chen, Meiling Dong, Anlong Xu, Shengfeng Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
ApeC
ACP
microbial binding
PGN
NF-κB
TRAF6
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.715245/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.715245/full

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