Innovations in the quantitative virus outgrowth assay and its use in clinical trials

Abstract A robust measure of the size of the latent HIV reservoir is essential to quantifying the effect of interventions designed to deplete the pool of reactivatable, replication competent proviruses. In addition to the ability to measure a biologically relevant parameter, any assay designed to be...

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Bibliographic Details
Main Authors: Nicholas J. Norton, Axel Fun, Mikaila Bandara, Mark R. Wills, Hoi Ping Mok, Andrew M. L. Lever
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Retrovirology
Subjects:
HIV
Online Access:http://link.springer.com/article/10.1186/s12977-017-0381-2