The ER Stress/UPR Axis in Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis

Cellular protein homeostasis in the lungs is constantly disrupted by recurrent exposure to various external and internal stressors, which may cause considerable protein secretion pressure on the endoplasmic reticulum (ER), resulting in the survival and differentiation of these cell types to meet the...

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Main Authors: Mahmoud Aghaei, Sanaz Dastghaib, Sajjad Aftabi, Mohamad-Reza Aghanoori, Javad Alizadeh, Pooneh Mokarram, Parvaneh Mehrbod, Milad Ashrafizadeh, Ali Zarrabi, Kielan Darcy McAlinden, Mathew Suji Eapen, Sukhwinder Singh Sohal, Pawan Sharma, Amir A. Zeki, Saeid Ghavami
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Life
Subjects:
UPR
Online Access:https://www.mdpi.com/2075-1729/11/1/1