Autophosphorylation and Self-Activation of DNA-Dependent Protein Kinase
The DNA-dependent protein kinase catalytic subunit (DNA-PKcs), a member of the phosphatidylinositol 3-kinase-related kinase family, phosphorylates serine and threonine residues of substrate proteins in the presence of the Ku complex and double-stranded DNA. Although it has been established that DNA-...
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Format: | Article |
Language: | English |
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MDPI AG
2021-07-01
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Series: | Genes |
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Online Access: | https://www.mdpi.com/2073-4425/12/7/1091 |