Degeneration of saccular hair cells caused by MITF gene mutation

Degeneration of saccular hair cells caused by MITF gene mutation

Abstract Background Waardenburg syndrome (WS) is the consequence of an inherited autosomal dominant mutation which causes the early degeneration of intermediate cells of cochlear stria vascularis (SV) and profound hearing loss. Patients with WS may also experience primary vestibular symptoms. Most o...

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Bibliographic Details
Main Authors: Yi Du, Li-li Ren, Qing-qing Jiang, Xing-jian Liu, Fei Ji, Yue Zhang, Shuo-long Yuan, Zi-Ming Wu, Wei-Wei Guo, Shi-Ming Yang
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Neural Development
Subjects:
MITF-M
Cochleosaccular degeneration
Hearing loss
Waardenburg syndrome
Intermediate cell
Pig
Online Access:http://link.springer.com/article/10.1186/s13064-019-0126-0

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http://link.springer.com/article/10.1186/s13064-019-0126-0

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