Transcription factor-associated combinatorial epigenetic pattern reveals higher transcriptional activity of TCF7L2-regulated intragenic enhancers

Transcription factor-associated combinatorial epigenetic pattern reveals higher transcriptional activity of TCF7L2-regulated intragenic enhancers

Abstract Background Recent studies have suggested that combinations of multiple epigenetic modifications are essential for controlling gene expression. Despite numerous computational approaches have been developed to decipher the combinatorial epigenetic patterns or “epigenetic code”, none of them h...

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Bibliographic Details
Main Authors: Qi Liu, Russell Bonneville, Tianbao Li, Victor X. Jin
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Genomics
Subjects:
T-cep
TCF7L2
Intragenic enhancer
PANC1
MCF7
Online Access:http://link.springer.com/article/10.1186/s12864-017-3764-9

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http://link.springer.com/article/10.1186/s12864-017-3764-9

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