The In Vitro–In Vivo Safety Confirmation of PEG-40 Hydrogenated Castor Oil as a Surfactant for Oral Nanoemulsion Formulation

The In Vitro–In Vivo Safety Confirmation of PEG-40 Hydrogenated Castor Oil as a Surfactant for Oral Nanoemulsion Formulation

Evaluation on the safety use of high concentration of polyoxyl 40 (PEG-40) hydrogenated castor oil as a surfactant for oral nanoemulsion was performed in Webster mice. As previously reported, nearly 20% of PEG-40 hydrogenated castor oil was used to emulsify the glyceryl monooleate (GMO) as an oil to...

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Bibliographic Details
Main Authors: Heni Rachmawati, Miranti Anggraeni Novel, Sri Ayu, Guntur Berlian, Olivia Mayasari Tandrasasmita, Raymond Rubianto Tjandrawinata, Kusnandar Anggadiredja
Format: Article
Language:English
Published: Österreichische Apotheker-Verlagsgesellschaft m. b. H. 2017-03-01
Series:Scientia Pharmaceutica
Subjects:
PEG-40 hydrogenated castor oil
self-nanoemulsion
glyceryl monooleate
oral delivery
cytotoxicity
Online Access:http://www.mdpi.com/2218-0532/85/2/18

Internet

http://www.mdpi.com/2218-0532/85/2/18

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