IRE1-XBP1 Pathway of the Unfolded Protein Response Is Required during Early Differentiation of C2C12 Myoblasts

IRE1-XBP1 Pathway of the Unfolded Protein Response Is Required during Early Differentiation of C2C12 Myoblasts

In skeletal muscle, myoblast differentiation results in the formation of multinucleated myofibers. Although recent studies have shown that unfolded protein responses (UPRs) play an important role in intracellular remodeling and contribute to skeletal muscle differentiation, the involvement of IRE1&a...

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Bibliographic Details
Main Authors: Yukako Tokutake, Keita Yamada, Satoko Hayashi, Wataru Arai, Takafumi Watanabe, Shinichi Yonekura
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:International Journal of Molecular Sciences
Subjects:
skeletal muscle differentiation
unfolded protein response (upr)
apoptosis
autophagy
Online Access:https://www.mdpi.com/1422-0067/21/1/182

Internet

https://www.mdpi.com/1422-0067/21/1/182

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