Safety and efficacy of alternative antibiotic regimens compared with 7 day injectable procaine benzylpenicillin and gentamicin for outpatient treatment of neonates and young infants with clinical signs of severe infection when referral is not possible: a randomised, open-label, equivalence trial

Background: Severe infections remain one of the main causes of neonatal deaths worldwide. Possible severe infection is diagnosed in young infants (aged 0–59 days) according to the presence of one or more clinical signs. The recommended treatment is hospital admission with 7–10 days of injectable ant...

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Main Authors: Prof. Abdullah H Baqui, DrPH, Prof. Samir K Saha, PhD, A S M Nawshad Uddin Ahmed, FCPS, Prof. Mohammad Shahidullah, FCPS, Iftekhar Quasem, MBBS, Daniel E Roth, PhD, A K M Samsuzzaman, DCH, Wazir Ahmed, DCH, Prof. S M Shahnawaz Bin Tabib, FCPS, Dipak K Mitra, PhD, Nazma Begum, MA, Maksuda Islam, BA, Arif Mahmud, MBBS, Mohammad Hefzur Rahman, MBBS, Mamun Ibne Moin, MA, Luke C Mullany, PhD, Prof. Simon Cousens, PhD, Shams El Arifeen, DrPH, Stephen Wall, MD, Neal Brandes, MA, Prof. Mathuram Santosham, MD, Prof. Robert E Black, MD
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:The Lancet Global Health
Online Access:http://www.sciencedirect.com/science/article/pii/S2214109X1470347X