MicroRNA-200c and microRNA- 141 are regulated by a FOXP3-KAT2B axis and associated with tumor metastasis in breast cancer

MicroRNA-200c and microRNA- 141 are regulated by a FOXP3-KAT2B axis and associated with tumor metastasis in breast cancer

Abstract Background Members of the microRNA (miR)-200 family, which are involved in tumor metastasis, have potential as cancer biomarkers, but their regulatory mechanisms remain elusive. Methods We investigated FOXP3-inducible breast cancer cells, Foxp3 heterozygous Scurfy mutant (Foxp3 sf/+ ) femal...

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Bibliographic Details
Main Authors: Guangxin Zhang, Wei Zhang, Bingjin Li, Erica Stringer-Reasor, Chengjing Chu, Liyan Sun, Sejong Bae, Dongquan Chen, Shi Wei, Kenneth Jiao, Wei-Hsiung Yang, Ranji Cui, Runhua Liu, Lizhong Wang
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Breast Cancer Research
Subjects:
microRNA
FOXP3
Breast cancer
Tumor metastasis
Circulation
Exosome
Online Access:http://link.springer.com/article/10.1186/s13058-017-0858-x

Internet

http://link.springer.com/article/10.1186/s13058-017-0858-x

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