Pharmacological Evaluation and Synthesis of New Sulfonamides Derivatives Based on 1,4-Benzodioxane

Pharmacological Evaluation and Synthesis of New Sulfonamides Derivatives Based on 1,4-Benzodioxane

We report here the synthesis of a series of N-aryl-2,3-dihydrobenzo[1,4]dioxine-6-sulfonamide and its N-substituted derivatives with benzyl chloride and ethyl iodide. Initially, 2,3-dihydrobenzo[1,4]dioxine-6-sulfonyl chloride (1) was subjected to react with various aryl amines (2a-e) to afford pare...

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Bibliographic Details
Main Authors: M. Irshad, M. A. Abbasi, Aziz-ur-Rehman, M. Akram, Q. Ali, S. Z. Siddiqui, M. Shahid, M. Ashraf, M. A. Lodhi, S. B. Jamal
Format: Article
Language:English
Published: National Centre of Excellence in Analytical Chemsitry 2018-12-01
Series:Pakistan Journal of Analytical & Environmental Chemistry
Subjects:
2
3-dihydrobenzo[1
4]dioxine-6-sulfonyl chloride
Lipoxygenase enzyme
1H-NMR
EI-MS
Antimicrobial and hemolytic activities
Online Access:http://www.pjaec.pk/index.php/pjaec/article/view/474/284

Internet

http://www.pjaec.pk/index.php/pjaec/article/view/474/284

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