Embedded-Culture of Pancreatic β-Cells Derived from Transgenic Mouse Insulinoma as a Potential Source for Xenotransplantation using a Diffusion Chamber

Embedded-culture of pancreatic β-cells derived from a transgenic mouse insulinoma (MIN6 cells) was studied in vitro and in vivo. The MIN6 cells were enmeshed in an agarose-PVMA-collagen matrix for long-term maintenance. The cells formed islet-like cell clusters (ICCs) in the mixed matrix. When 10 mm...

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Bibliographic Details
Main Authors: Hisako Ohgawara, Jun-Ichi Miyazaki, Sachiyo Karibe, Fumi Tashiro, Toshihiro Akaike, Yoko Hashimoto
Format: Article
Language:English
Published: SAGE Publishing 1995-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368979500400309